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Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azacitidine.
Visconte, V; Nawrocki, S T; Espitia, C M; Kelly, K R; Possemato, A; Beausoleil, S A; Han, Y; Carraway, H E; Nazha, A; Advani, A S; Maciejewski, J P; Sekeres, M A; Carew, J S.
Afiliación
  • Visconte V; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Nawrocki ST; Division of Hematology/Oncology, Cancer Therapy and Research Center at The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Espitia CM; Division of Hematology/Oncology, Cancer Therapy and Research Center at The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Kelly KR; USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
  • Possemato A; Cell Signaling Technology, Danvers, MA, USA.
  • Beausoleil SA; Cell Signaling Technology, Danvers, MA, USA.
  • Han Y; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Carraway HE; Leukemia Program, Department of Hematology/Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Nazha A; Leukemia Program, Department of Hematology/Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Advani AS; Leukemia Program, Department of Hematology/Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Maciejewski JP; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Sekeres MA; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Carew JS; Leukemia Program, Department of Hematology/Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Leukemia ; 30(5): 1190-4, 2016 05.
Article en En | MEDLINE | ID: mdl-26369982
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Azacitidina / Leucemia Mieloide Aguda / Ciclopentanos / Proteómica / Proteínas de Neoplasias Límite: Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirimidinas / Azacitidina / Leucemia Mieloide Aguda / Ciclopentanos / Proteómica / Proteínas de Neoplasias Límite: Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos