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Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
Day, Felix R; Hinds, David A; Tung, Joyce Y; Stolk, Lisette; Styrkarsdottir, Unnur; Saxena, Richa; Bjonnes, Andrew; Broer, Linda; Dunger, David B; Halldorsson, Bjarni V; Lawlor, Debbie A; Laval, Guillaume; Mathieson, Iain; McCardle, Wendy L; Louwers, Yvonne; Meun, Cindy; Ring, Susan; Scott, Robert A; Sulem, Patrick; Uitterlinden, André G; Wareham, Nicholas J; Thorsteinsdottir, Unnur; Welt, Corrine; Stefansson, Kari; Laven, Joop S E; Ong, Ken K; Perry, John R B.
Afiliación
  • Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
  • Hinds DA; 23andMe Inc., Mountain View, California 94043, USA.
  • Tung JY; 23andMe Inc., Mountain View, California 94043, USA.
  • Stolk L; Department of Internal Medicine, Erasmus MC, Rotterdam 3015 GE, The Netherlands.
  • Styrkarsdottir U; deCODE Genetics/Amgen, Sturlugata 8, IS-101 Reykjavik, Iceland.
  • Saxena R; Department of Anaesthesia and Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Bjonnes A; Department of Anaesthesia and Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
  • Broer L; Department of Internal Medicine, Erasmus MC, Rotterdam 3015 GE, The Netherlands.
  • Dunger DB; Department of Paediatrics, University of Cambridge School of Clinical Medicine, Box 181, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
  • Halldorsson BV; deCODE Genetics/Amgen, Sturlugata 8, IS-101 Reykjavik, Iceland.
  • Lawlor DA; Institute of Biomedical and Neural Engineering, School of Science and Engineering, Reykjavík University, Menntavegur 1, 101 Reykjavík, Iceland.
  • Laval G; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK.
  • Mathieson I; School of Social and Community Medicine, University of Bristol, Oakfield House, Bristol BS8 2BN, UK.
  • McCardle WL; Human Evolutionary Genetics, CNRS URA3012 Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex 15, France.
  • Louwers Y; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Meun C; School of Social and Community Medicine, University of Bristol, Oakfield House, Bristol BS8 2BN, UK.
  • Ring S; Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam, 3015 GE, The Netherlands.
  • Scott RA; Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam, 3015 GE, The Netherlands.
  • Sulem P; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK.
  • Uitterlinden AG; School of Social and Community Medicine, University of Bristol, Oakfield House, Bristol BS8 2BN, UK.
  • Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
  • Thorsteinsdottir U; deCODE Genetics/Amgen, Sturlugata 8, IS-101 Reykjavik, Iceland.
  • Welt C; Department of Internal Medicine, Erasmus MC, Rotterdam 3015 GE, The Netherlands.
  • Stefansson K; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
  • Laven JSE; deCODE Genetics/Amgen, Sturlugata 8, IS-101 Reykjavik, Iceland.
  • Ong KK; Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland.
  • Perry JRB; Division of Endocrinology, Metabolism and Diabetes, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA.
Nat Commun ; 6: 8464, 2015 Sep 29.
Article en En | MEDLINE | ID: mdl-26416764
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Selección Genética / Población Blanca Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Selección Genética / Población Blanca Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido