Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation.

Tropberger, Philipp; Mercier, Alexandre; Robinson, Margaret; Zhong, Weidong; Ganem, Don E; Holdorf, Meghan

Tropberger, Philipp; Mercier, Alexandre; Robinson, Margaret; Zhong, Weidong; Ganem, Don E; Holdorf, Meghan.

Afiliación

Tropberger P; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608 don.ganem@novartis.com philipp.tropberger@novartis.com.
Mercier A; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
Robinson M; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
Zhong W; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
Ganem DE; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608 don.ganem@novartis.com philipp.tropberger@novartis.com.
Holdorf M; Department of Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.

Proc Natl Acad Sci U S A ; 112(42): E5715-24, 2015 Oct 20.

Article en En | MEDLINE | ID: mdl-26438841

Asunto(s)

Cromatina/metabolismo; ADN Viral/genética; Epigénesis Genética; Virus de la Hepatitis B/genética; Histonas/metabolismo; Plásmidos/metabolismo; Células Hep G2; Humanos; Transcripción Genética

Palabras clave

HBV; cccDNA; chromatin; epigenetics; hepatitis B virus

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plásmidos / ADN Viral / Cromatina / Histonas / Virus de la Hepatitis B / Epigénesis Genética Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google