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Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Zhang, Jing; Yang, Qingyi; Cross, Jason B; Romero, Jan Antoinette C; Poutsiaka, Katherine M; Epie, Felix; Bevan, Douglas; Wang, Bin; Zhang, Yanzhi; Chavan, Ajit; Zhang, Xin; Moy, Terence; Daniel, Anu; Nguyen, Kien; Chamberlain, Brian; Carter, Nicole; Shotwell, Joseph; Silverman, Jared; Metcalf, Chester A; Ryan, Dominic; Lippa, Blaise; Dolle, Roland E.
Afiliación
  • Zhang J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Yang Q; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Cross JB; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Romero JA; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Poutsiaka KM; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Epie F; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Bevan D; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Wang B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Zhang Y; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Chavan A; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Zhang X; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Moy T; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Daniel A; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Nguyen K; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Chamberlain B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Carter N; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Shotwell J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Silverman J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Metcalf CA; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Ryan D; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Lippa B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Dolle RE; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
J Med Chem ; 58(21): 8503-12, 2015 Nov 12.
Article en En | MEDLINE | ID: mdl-26460684
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Urea / Girasa de ADN / Staphylococcus aureus Resistente a Meticilina / Inhibidores de Topoisomerasa II / Indoles Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Urea / Girasa de ADN / Staphylococcus aureus Resistente a Meticilina / Inhibidores de Topoisomerasa II / Indoles Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos