Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis.

Valentijn, A J; Saretzki, G; Tempest, N; Critchley, H O D; Hapangama, D K

Valentijn, A J; Saretzki, G; Tempest, N; Critchley, H O D; Hapangama, D K.

Afiliación

Valentijn AJ; Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L8 7SS, UK.
Saretzki G; Institute for Cell and Molecular Biosciences and Institute for Ageing, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK.
Tempest N; Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L8 7SS, UK Liverpool Women's Hospital NHS Foundation Trust, Liverpool, UK.
Critchley HO; MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh EH16 4TJ, UK.
Hapangama DK; Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L8 7SS, UK Liverpool Women's Hospital NHS Foundation Trust, Liverpool, UK dharani@liv.ac.uk.

Hum Reprod ; 30(12): 2816-28, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26498179

Asunto(s)

Proliferación Celular/fisiología; Endometriosis/metabolismo; Endometrio/metabolismo; Células Epiteliales/metabolismo; Telomerasa/metabolismo; Adolescente; Adulto; Proliferación Celular/efectos de los fármacos; Endometriosis/patología; Endometrio/efectos de los fármacos; Endometrio/patología; Células Epiteliales/patología; Femenino; Antagonistas de Hormonas/farmacología; Humanos; Persona de Mediana Edad; Mifepristona/farmacología; Progesterona/sangre; Estudios Prospectivos; Receptores de Progesterona/antagonistas & inhibidores; Células del Estroma/efectos de los fármacos; Células del Estroma/metabolismo; Células del Estroma/patología; Adulto Joven

Palabras clave

3D culture; Imetelstat; cell culture; endometrial epithelium; endometriosis; endometrium; progesterone; proliferation; telomerase; telomere length

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Telomerasa / Proliferación Celular / Endometriosis / Endometrio / Células Epiteliales Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Middle aged Idioma: En Revista: Hum Reprod Asunto de la revista: MEDICINA REPRODUTIVA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido

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