A polydopamine nanosphere based highly sensitive and selective aptamer cytosensor with enzyme amplification.
Chem Commun (Camb)
; 52(2): 406-9, 2016 Jan 07.
Article
en En
| MEDLINE
| ID: mdl-26526224
ABSTRACT
With CCRF-CEM as the model cell, a highly sensitive and selective cytosensor was developed by taking advantage of polydopamine nanospheres for the first time. The strategies of aptamer/membrane protein recognition and Exonuclease III assisted cycle amplification were used for improving selectivity and sensitivity. The detection of limit reached was as low as 15 cells per mL.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Técnicas Biosensibles
/
Aptámeros de Nucleótidos
/
Exodesoxirribonucleasas
/
Nanosferas
/
Indoles
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2016
Tipo del documento:
Article