Feasibility of an exercise programme in elderly patients undergoing allogeneic stem cell transplantation - a pilot study.
Eur J Cancer Care (Engl)
; 25(5): 839-48, 2016 Sep.
Article
en En
| MEDLINE
| ID: mdl-26526286
ABSTRACT
It has been demonstrated that physical exercise benefits younger patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT). We designed a prospective pilot study investigating whether elderly patients (>60 years) would also be able to participate in such a programme. It consisted of physiotherapist-supervised alternating endurance and resistance workouts on 6 of 7 days a week. Sixteen consecutive patients undergoing allo-HSCT were enrolled into the study. The median age was 64.5 years. Twelve patients participated in the programme until the time of discharge (75%) from the transplant unit. Therefore, the predefined criteria regarding feasibility were met. The reason for drop out was transplantation associated mortality in all patients (n = 4). Adherence was very good with a median of 85% attended training sessions. No adverse events were recorded. The endurance capacity dropped by 7% and lower extremity strength improved by 2% over time. Quality of life decreased during the study period, with global health being significantly worse at the time of discharge. In conclusion, a combined and intensified strength and endurance exercise programme is feasible and safe in a population of elderly patients undergoing allo-HSCT. Further research should focus on exploring effect sizes of such an intervention by conducting randomised controlled trials.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
11_ODS3_cobertura_universal
/
2_ODS3
Problema de salud:
11_delivery_arrangements
/
2_cobertura_universal
Asunto principal:
Trasplante de Células Madre Hematopoyéticas
/
Neoplasias Hematológicas
/
Terapia por Ejercicio
Tipo de estudio:
Clinical_trials
/
Evaluation_studies
/
Observational_studies
Aspecto:
Implementation_research
/
Patient_preference
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur J Cancer Care (Engl)
Asunto de la revista:
ENFERMAGEM
/
NEOPLASIAS
Año:
2016
Tipo del documento:
Article
País de afiliación:
Alemania