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Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB.
Buontempo, Francesca; Orsini, Ester; Lonetti, Annalisa; Cappellini, Alessandra; Chiarini, Francesca; Evangelisti, Camilla; Evangelisti, Cecilia; Melchionda, Fraia; Pession, Andrea; Bertaina, Alice; Locatelli, Franco; Bertacchini, Jessika; Neri, Luca Maria; McCubrey, James A; Martelli, Alberto Maria.
Afiliación
  • Buontempo F; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
  • Orsini E; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
  • Lonetti A; Pediatric Oncology and Hematology Unit "Lalla Seràgnoli", S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Cappellini A; Department of Human Social and Health Sciences, Campus Folcara, University of Cassino, Cassino, Italy.
  • Chiarini F; Muscoloskeletal Cell Biology Laboratory, IOR, Bologna, Italy.
  • Evangelisti C; Institute of Molecular Genetics, National Research Council-Rizzoli Orthopedic Institute, Bologna, Italy.
  • Evangelisti C; Muscoloskeletal Cell Biology Laboratory, IOR, Bologna, Italy.
  • Melchionda F; Institute of Molecular Genetics, National Research Council-Rizzoli Orthopedic Institute, Bologna, Italy.
  • Pession A; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
  • Bertaina A; Pediatric Oncology and Hematology Unit "Lalla Seràgnoli", S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Locatelli F; Pediatric Oncology and Hematology Unit "Lalla Seràgnoli", S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Bertacchini J; Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Neri LM; Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • McCubrey JA; Department of Surgery, Medicine, Odontostomatology and Morphological Sciences, University of Modena, Modena, Italy.
  • Martelli AM; Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Oncotarget ; 7(2): 1323-40, 2016 Jan 12.
Article en En | MEDLINE | ID: mdl-26593250
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Apoptosis / Factor de Transcripción ReIA / Bortezomib / Proteínas de Choque Térmico / Naftiridinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Apoptosis / Factor de Transcripción ReIA / Bortezomib / Proteínas de Choque Térmico / Naftiridinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Italia