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Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition.
Henssen, Anton; Althoff, Kristina; Odersky, Andrea; Beckers, Anneleen; Koche, Richard; Speleman, Frank; Schäfers, Simon; Bell, Emma; Nortmeyer, Maike; Westermann, Frank; De Preter, Katleen; Florin, Alexandra; Heukamp, Lukas; Spruessel, Annika; Astrahanseff, Kathy; Lindner, Sven; Sadowski, Natalie; Schramm, Alexander; Astorgues-Xerri, Lucile; Riveiro, Maria E; Eggert, Angelika; Cvitkovic, Esteban; Schulte, Johannes H.
Afiliación
  • Henssen A; Molecular Pharmacology & Chemistry Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany. henssena@mskcc.org.
  • Althoff K; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany. German Consortium for Translational Cancer Research (DKTK), Partner Site Essen/Duesseldorf, Essen, Germany.
  • Odersky A; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.
  • Beckers A; Center of Medical Genetics Ghent (CMGG), Ghent University Hospital, Ghent, Belgium.
  • Koche R; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Speleman F; Center of Medical Genetics Ghent (CMGG), Ghent University Hospital, Ghent, Belgium.
  • Schäfers S; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany. German Consortium for Translational Cancer Research (DKTK), Partner Site Essen/Duesseldorf, Essen, Germany.
  • Bell E; Neuroblastoma Genomics, B087, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Nortmeyer M; Neuroblastoma Genomics, B087, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Westermann F; Neuroblastoma Genomics, B087, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • De Preter K; Center of Medical Genetics Ghent (CMGG), Ghent University Hospital, Ghent, Belgium.
  • Florin A; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
  • Heukamp L; New Oncology, Köln, Germany. Institut für Hämatopathologie Hamburg, Hamburg, Germany.
  • Spruessel A; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.
  • Astrahanseff K; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Lindner S; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.
  • Sadowski N; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.
  • Schramm A; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany.
  • Astorgues-Xerri L; Oncology Therapeutic Development, Clichy, France.
  • Riveiro ME; Oncology Therapeutic Development, Clichy, France.
  • Eggert A; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Cvitkovic E; Oncology Therapeutic Development, Clichy, France. Oncoethix, Lausanne, Switzerland.
  • Schulte JH; Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Essen, Germany. German Consortium for Translational Cancer Research (DKTK), Partner Site Essen/Duesseldorf, Essen, Germany. Neuroblastoma Genomics, B087, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Clin Cancer Res ; 22(10): 2470-81, 2016 05 15.
Article en En | MEDLINE | ID: mdl-26631615
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcripción Genética / Proteína Proto-Oncogénica N-Myc / Proteínas del Tejido Nervioso / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transcripción Genética / Proteína Proto-Oncogénica N-Myc / Proteínas del Tejido Nervioso / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Alemania