Fabrication of a Flexible Amperometric Glucose Sensor Using Additive Processes.
ECS J Solid State Sci Technol
; 4(4): P3069-P3074, 2015.
Article
en En
| MEDLINE
| ID: mdl-26634186
ABSTRACT
This study details the use of printing and other additive processes to fabricate a novel amperometric glucose sensor. The sensor was fabricated using a Au coated 12.7 µm thick polyimide substrate as a starting material, where micro-contact printing, electrochemical plating, chloridization, electrohydrodynamic jet (e-jet) printing, and spin coating were used to pattern, deposit, chloridize, print, and coat functional materials, respectively. We have found that e-jet printing was effective for the deposition and patterning of glucose oxidase inks with lateral feature sizes between ~5 to 1000 µm in width, and that the glucose oxidase was still active after printing. The thickness of the permselective layer was optimized to obtain a linear response for glucose concentrations up to 32 mM and no response to acetaminophen, a common interfering compound, was observed. The use of such thin polyimide substrates allow wrapping of the sensors around catheters with high radius of curvature ~250 µm, where additive and microfabrication methods may allow significant cost reductions.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
ECS J Solid State Sci Technol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos