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Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.
Bigdeli, Tim B; Ripke, Stephan; Bacanu, Silviu-Alin; Lee, Sang Hong; Wray, Naomi R; Gejman, Pablo V; Rietschel, Marcella; Cichon, Sven; St Clair, David; Corvin, Aiden; Kirov, George; McQuillin, Andrew; Gurling, Hugh; Rujescu, Dan; Andreassen, Ole A; Werge, Thomas; Blackwood, Douglas H R; Pato, Carlos N; Pato, Michele T; Malhotra, Anil K; O'Donovan, Michael C; Kendler, Kenneth S; Fanous, Ayman H.
Afiliación
  • Bigdeli TB; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia.
  • Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts.
  • Bacanu SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Lee SH; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia.
  • Wray NR; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
  • Gejman PV; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
  • Rietschel M; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois.
  • Cichon S; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois.
  • St Clair D; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Corvin A; Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Kirov G; Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • McQuillin A; Department of Genomics, Life and Brain Center, Bonn, Germany.
  • Gurling H; Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany.
  • Rujescu D; University of Aberdeen, Institute of Medical Sciences, Aberdeen, Scotland, United Kingdom.
  • Andreassen OA; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland.
  • Werge T; MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Blackwood DH; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, United Kingdom.
  • Pato CN; Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, United Kingdom.
  • Pato MT; Department of Psychiatry, University of Halle, Halle, Germany.
  • Malhotra AK; Department of Psychiatry, University of Munich, Munich, Germany.
  • O'Donovan MC; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Kendler KS; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
  • Fanous AH; Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Services Copenhagen, Denmark.
Am J Med Genet B Neuropsychiatr Genet ; 171B(2): 276-89, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26663532
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Predisposición Genética a la Enfermedad / Herencia Multifactorial / Estudio de Asociación del Genoma Completo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Med Genet B Neuropsychiatr Genet Asunto de la revista: GENETICA MEDICA / NEUROLOGIA / PSIQUIATRIA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Predisposición Genética a la Enfermedad / Herencia Multifactorial / Estudio de Asociación del Genoma Completo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Med Genet B Neuropsychiatr Genet Asunto de la revista: GENETICA MEDICA / NEUROLOGIA / PSIQUIATRIA Año: 2016 Tipo del documento: Article