Your browser doesn't support javascript.
loading
Effect of high energy X-ray irradiation on the nano-mechanical properties of human enamel and dentine.
Liang, Xue; Zhang, Jing Yang; Cheng, Iek Ka; Li, Ji Yao.
Afiliación
  • Liang X; State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
  • Zhang JY; State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
  • Cheng IK; State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
  • Li JY; West China School of Stomatology, Sichuan University, Chengdu, China.
Braz Oral Res ; 302016.
Article en En | MEDLINE | ID: mdl-26676192
ABSTRACT
Radiotherapy for malignancies in the head and neck can cause common complications that can result in tooth damage that are also known as radiation caries. The aim of this study was to examine damage to the surface topography and calculate changes in friction behavior and the nano-mechanical properties (elastic modulus, nanohardness and friction coefficient) of enamel and dentine from extracted human third molars caused by exposure to radiation. Enamel and dentine samples from 50 human third molars were randomly assigned to four test groups or a control group. The test groups were exposed to high energy X-rays at 2 Gy/day, 5 days/week for 5 days (10 Gy group), 15 days (30 Gy group), 25 days (50 Gy group), 35 days (70 Gy group); the control group was not exposed. The nanohardness, elastic modulus, and friction coefficient were analyzed using a Hysitron Triboindenter. The nano-mechanical properties of both enamel and dentine showed significant dose-response relationships. The nanohardness and elastic modulus were most variable between 30-50 Gy, while the friction coefficient was most variable between 0-10 Gy for dentine and 30-50 Gy for enamel. After exposure to X-rays, the fracture resistance of the teeth clearly decreased (rapidly increasing friction coefficient with increasing doses under the same load), and they were more fragile. These nano-mechanical changes in dental hard tissue may increase the susceptibility to caries. Radiotherapy caused nano-mechanical changes in dentine and enamel that were dose related. The key doses were 30-50 Gy and the key time points occurred during the 15th-25th days of treatment, which is when application of measures to prevent radiation caries should be considered.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos por Radiación / Radioterapia de Alta Energía / Esmalte Dental / Dentina Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Braz Oral Res Asunto de la revista: ODONTOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos por Radiación / Radioterapia de Alta Energía / Esmalte Dental / Dentina Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Braz Oral Res Asunto de la revista: ODONTOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: China
...