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A peptide-linked recombinant glucocerebrosidase for targeted neuronal delivery: Design, production, and assessment.
Gramlich, Paul A; Westbroek, Wendy; Feldman, Ricardo A; Awad, Ola; Mello, Nicholas; Remington, Mary P; Sun, Ying; Zhang, Wujuan; Sidransky, Ellen; Betenbaugh, Michael J; Fishman, Paul S.
Afiliación
  • Gramlich PA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Research Service, Veterans Affairs Maryland Health Care Service, Baltimore, MD, USA. Electronic address: pgramli1@jhu.edu.
  • Westbroek W; Section on Molecular Neurogenetics, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Feldman RA; Department of Microbiology and Immunology, University of Maryland School of Medicine, MD, USA.
  • Awad O; Department of Microbiology and Immunology, University of Maryland School of Medicine, MD, USA.
  • Mello N; Research Service, Veterans Affairs Maryland Health Care Service, Baltimore, MD, USA; Department of Molecular Medicine, University of Maryland School of Medicine, MD, USA.
  • Remington MP; Research Service, Veterans Affairs Maryland Health Care Service, Baltimore, MD, USA.
  • Sun Y; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Zhang W; Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Sidransky E; Section on Molecular Neurogenetics, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Betenbaugh MJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
  • Fishman PS; Research Service, Veterans Affairs Maryland Health Care Service, Baltimore, MD, USA; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.
J Biotechnol ; 221: 1-12, 2016 Mar 10.
Article en En | MEDLINE | ID: mdl-26795355
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Proteínas Recombinantes / Glucosilceramidasa / Neuronas Límite: Humans Idioma: En Revista: J Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Proteínas Recombinantes / Glucosilceramidasa / Neuronas Límite: Humans Idioma: En Revista: J Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2016 Tipo del documento: Article