[Impact of maternal obesity and diabetes on placental function]. / Impact de l'obésité et du diabète maternels sur la fonction placentaire.
Med Sci (Paris)
; 32(1): 66-73, 2016 Jan.
Article
en Fr
| MEDLINE
| ID: mdl-26850609
ABSTRACT
Located at the feto-maternal interface, the placenta is involved in exchange, endocrine and immune functions, which impact fetal development. In contact with the maternal environment, this organ is sensitive to metabolic disorders as over-nutrition, obesity or diabetes. The alteration of blood parameters associated with these pathologies affects placental histology, vascularization and nutrient transfers and, according to the types of troubles, induces local inflammation or hypoxia. These placental changes lead to disturbance of development and fetal growth, which increase the risk of pathologies in offspring in adulthood. The placenta thus appears as a crucial player in the fetal programming.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Placenta
/
Complicaciones del Embarazo
/
Diabetes Mellitus
/
Obesidad
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
Fr
Revista:
Med Sci (Paris)
Asunto de la revista:
MEDICINA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Francia