CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425.

He, Bing; Li, Ting; Guan, Lei; Liu, Fang-E; Chen, Xue-Mei; Zhao, Jing; Lin, Song; Liu, Zhi-Zhen; Zhang, Hu-Qin

He, Bing; Li, Ting; Guan, Lei; Liu, Fang-E; Chen, Xue-Mei; Zhao, Jing; Lin, Song; Liu, Zhi-Zhen; Zhang, Hu-Qin.

Afiliación

He B; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Li T; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Guan L; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Liu FE; The Center of Basic Medicine Teaching Experiments, School of Basic Medicine, Fourth Military Medicine University (FMMU), Xi'an 710032, P.R. China.
Chen XM; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Zhao J; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Lin S; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Liu ZZ; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Zhang HQ; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.

Oncotarget ; 7(7): 8078-89, 2016 Feb 16.

Article en En | MEDLINE | ID: mdl-26882563

Asunto(s)

Carcinoma Hepatocelular/genética; Regulación Neoplásica de la Expresión Génica; Genes Supresores de Tumor; Neoplasias Hepáticas/genética; MicroARNs/genética; alfa Catenina/genética; Regiones no Traducidas 3'/genética; Animales; Apoptosis; Western Blotting; Carcinoma Hepatocelular/metabolismo; Carcinoma Hepatocelular/patología; Estudios de Casos y Controles; Ciclo Celular; Movimiento Celular; Proliferación Celular; Técnica del Anticuerpo Fluorescente; Estudios de Seguimiento; Humanos; Técnicas para Inmunoenzimas; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patología; Masculino; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; ARN Mensajero/genética; Reacción en Cadena en Tiempo Real de la Polimerasa; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto; alfa Catenina/metabolismo

Palabras clave

CTNNA3; HCC; invasion; miR-425; proliferation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_digestive_diseases / 6_liver_cancer Asunto principal: Regulación Neoplásica de la Expresión Génica / Genes Supresores de Tumor / Carcinoma Hepatocelular / MicroARNs / Alfa Catenina / Neoplasias Hepáticas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article

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