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Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.
Wagner, Tobias; Greschik, Holger; Burgahn, Teresa; Schmidtkunz, Karin; Schott, Anne-Kathrin; McMillan, Joel; Baranauskiene, Lina; Xiong, Yan; Fedorov, Oleg; Jin, Jian; Oppermann, Udo; Matulis, Daumantas; Schüle, Roland; Jung, Manfred.
Afiliación
  • Wagner T; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg 79104, Germany.
  • Greschik H; Department of Urology and Center for Clinical Research, University Freiburg Medical Center, Freiburg 79106, Germany.
  • Burgahn T; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg 79104, Germany.
  • Schmidtkunz K; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg 79104, Germany.
  • Schott AK; Department of Urology and Center for Clinical Research, University Freiburg Medical Center, Freiburg 79106, Germany.
  • McMillan J; Department of Urology and Center for Clinical Research, University Freiburg Medical Center, Freiburg 79106, Germany.
  • Baranauskiene L; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, Vilnius 02241, Lithuania.
  • Xiong Y; Department of Structural and Chemical Biology, Department of Oncological Sciences, Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA.
  • Fedorov O; Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Target Discovery Institute (TDI), Oxford OX3 7FZ, UK.
  • Jin J; Department of Structural and Chemical Biology, Department of Oncological Sciences, Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA.
  • Oppermann U; Structural Genomics Consortium, Botnar Research Center, NIHR Oxford BRU, University of Oxford, Oxford OX3 7LD, UK.
  • Matulis D; Department of Biothermodynamics and Drug Design, Institute of Biotechnology, Vilnius University, Vilnius 02241, Lithuania.
  • Schüle R; Department of Urology and Center for Clinical Research, University Freiburg Medical Center, Freiburg 79106, Germany German Cancer Consortium (DKTK), Freiburg, Germany BIOSS Centre of Biological Signalling Studies, University of Freiburg, 79106 Freiburg, Germany.
  • Jung M; Institute of Pharmaceutical Sciences, University of Freiburg, Freiburg 79104, Germany BIOSS Centre of Biological Signalling Studies, University of Freiburg, 79106 Freiburg, Germany German Cancer Research Centre (DKFZ), Heidelberg, Germany manfred.jung@pharmazie.uni-freiburg.de.
Nucleic Acids Res ; 44(9): e88, 2016 05 19.
Article en En | MEDLINE | ID: mdl-26893353
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Histonas / Procesamiento Proteico-Postraduccional / Proteínas de Ciclo Celular / Epigénesis Genética / Proteínas Asociadas a Microtúbulos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Histonas / Procesamiento Proteico-Postraduccional / Proteínas de Ciclo Celular / Epigénesis Genética / Proteínas Asociadas a Microtúbulos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2016 Tipo del documento: Article País de afiliación: Alemania