Cancer TARGETases: DSB repair as a pharmacological target.

Samadder, Pounami; Aithal, Rakesh; Belan, Ondrej; Krejci, Lumir

Samadder, Pounami; Aithal, Rakesh; Belan, Ondrej; Krejci, Lumir.

Afiliación

Samadder P; National Centre for Biomolecular Research, Masaryk University, 62500 Brno, Czech Republic; International Clinical Research Center, Center for Biomolecular and Cellular Engineering, St. Anne's University Hospital in Brno, 60200 Brno, Czech Republic.
Aithal R; National Centre for Biomolecular Research, Masaryk University, 62500 Brno, Czech Republic; Department of Biology, Masaryk University, 62500 Brno, Czech Republic.
Belan O; Department of Biology, Masaryk University, 62500 Brno, Czech Republic.
Krejci L; National Centre for Biomolecular Research, Masaryk University, 62500 Brno, Czech Republic; International Clinical Research Center, Center for Biomolecular and Cellular Engineering, St. Anne's University Hospital in Brno, 60200 Brno, Czech Republic; Department of Biology, Masaryk University, 62500 Br

Pharmacol Ther ; 161: 111-131, 2016 05.

Article en En | MEDLINE | ID: mdl-26899499

Asunto(s)

Roturas del ADN de Doble Cadena/efectos de los fármacos; Reparación del ADN/efectos de los fármacos; Terapia Molecular Dirigida/métodos; Neoplasias/tratamiento farmacológico; Neoplasias/enzimología; Animales; Humanos

Palabras clave

Cancer; DSB repair; Genome instability; Helicases; Kinases; Nucleases

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reparación del ADN / Roturas del ADN de Doble Cadena / Terapia Molecular Dirigida / Neoplasias Límite: Animals / Humans Idioma: En Revista: Pharmacol Ther Año: 2016 Tipo del documento: Article País de afiliación: República Checa

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