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Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas.
Ebbesen, Saya H; Scaltriti, Maurizio; Bialucha, Carl U; Morse, Natasha; Kastenhuber, Edward R; Wen, Hannah Y; Dow, Lukas E; Baselga, José; Lowe, Scott W.
Afiliación
  • Ebbesen SH; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Scaltriti M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Bialucha CU; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724;
  • Morse N; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Kastenhuber ER; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Wen HY; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Dow LE; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065;
  • Baselga J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Department of Medicine, Weill Cornell Medicine, New York, NY 10065;
  • Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Howard Hughes Medical Institute, New York, NY 10065 lowes@mskcc.org.
Proc Natl Acad Sci U S A ; 113(11): 3030-5, 2016 Mar 15.
Article en En | MEDLINE | ID: mdl-26929372
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor ErbB-2 / Sistema de Señalización de MAP Quinasas / Fosfohidrolasa PTEN / Neoplasias Mamarias Experimentales / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor ErbB-2 / Sistema de Señalización de MAP Quinasas / Fosfohidrolasa PTEN / Neoplasias Mamarias Experimentales / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article