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The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux.
Yaron, Jordan R; Rao, Mounica Y; Gangaraju, Sandhya; Zhang, Liqiang; Kong, Xiangxing; Su, Fengyu; Tian, Yanqing; Glenn, Honor L; Meldrum, Deirdre R.
Afiliación
  • Yaron JR; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA; Biological Design Graduate Program, School of Biological and Health Systems Engineering, Ira A. Fulton Schools of Engineering, Arizona State University, Tempe, AZ, 85287, USA.
  • Rao MY; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Gangaraju S; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Zhang L; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Kong X; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Su F; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Tian Y; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Glenn HL; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA.
  • Meldrum DR; Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA. Electronic address: Deirdre.Meldrum@asu.edu.
Biochem Biophys Res Commun ; 472(3): 545-50, 2016 Apr 08.
Article en En | MEDLINE | ID: mdl-26970308
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potasio / Sulfonamidas / Transducción de Señal / Inflamasomas / Piroptosis / Indoles Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potasio / Sulfonamidas / Transducción de Señal / Inflamasomas / Piroptosis / Indoles Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos