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Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1).
Guo, Junqing; Watterson, Scott H; Spergel, Steven H; Kempson, James; Langevine, Charles M; Shen, Ding Ren; Yarde, Melissa; Cvijic, Mary Ellen; Banas, Dana; Liu, Richard; Suchard, Suzanne J; Gillooly, Kathleen; Taylor, Tracy; Rex-Rabe, Sandra; Shuster, David J; McIntyre, Kim W; Cornelius, Georgia; D'Arienzo, Celia; Marino, Anthony; Balimane, Praveen; Salter-Cid, Luisa; McKinnon, Murray; Barrish, Joel C; Carter, Percy H; Pitts, William J; Xie, Jenny; Dyckman, Alaric J.
Afiliación
  • Guo J; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States. Electronic address: junqing.guo@bms.com.
  • Watterson SH; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Spergel SH; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Kempson J; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Langevine CM; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Shen DR; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Yarde M; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Cvijic ME; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Banas D; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Liu R; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Suchard SJ; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Gillooly K; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Taylor T; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Rex-Rabe S; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Shuster DJ; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • McIntyre KW; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Cornelius G; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • D'Arienzo C; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Marino A; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Balimane P; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Salter-Cid L; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • McKinnon M; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Barrish JC; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Carter PH; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Pitts WJ; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Xie J; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
  • Dyckman AJ; Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, United States.
Bioorg Med Chem Lett ; 26(10): 2470-2474, 2016 05 15.
Article en En | MEDLINE | ID: mdl-27055941
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Experimental / Esfingosina / Relación Estructura-Actividad / Lisofosfolípidos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Experimental / Esfingosina / Relación Estructura-Actividad / Lisofosfolípidos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article