Evaluation of the ΔV 4D CT ventilation calculation method using in vivo xenon CT ventilation data and comparison to other methods.
J Appl Clin Med Phys
; 17(2): 550-560, 2016 03 08.
Article
en En
| MEDLINE
| ID: mdl-27074479
ABSTRACT
Ventilation distribution calculation using 4D CT has shown promising potential in several clinical applications. This study evaluated the direct geometric ventilation calculation method, namely the ΔV method, with xenon-enhanced CT (XeCT) ventilation data from four sheep, and compared it with two other published meth-ods, the Jacobian and the Hounsfield unit (HU) methods. Spearman correlation coefficient (SCC) and Dice similarity coefficient (DSC) were used for the evaluation and comparison. The average SCC with one standard deviation was 0.44 ± 0.13 with a range between 0.29 and 0.61 between the XeCT and ΔV ventilation distributions. The average DSC value for lower 30% ventilation volumes between the XeCT and ΔV ventilation distributions was 0.55 ± 0.07 with a range between 0.48 and 0.63. Ventilation difference introduced by deformable image registration errors improved with smoothing. In conclusion, ventilation distributions generated using ΔV-4D CT and deformable image registration are in reasonably agreement with the in vivo XeCT measured ventilation distribution.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Respiración
/
Xenón
/
Algoritmos
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Procesamiento de Imagen Asistido por Computador
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Ventilación Pulmonar
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Tomografía Computarizada Cuatridimensional
Tipo de estudio:
Evaluation_studies
Límite:
Animals
Idioma:
En
Revista:
J Appl Clin Med Phys
Asunto de la revista:
BIOFISICA
Año:
2016
Tipo del documento:
Article