Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process.
Carbohydr Polym
; 143: 84-9, 2016 Jun 05.
Article
en En
| MEDLINE
| ID: mdl-27083346
ABSTRACT
An environmentally sustainable and energy-efficient synthetic process has been developed to prepare hyaluronan-based nano-sized material. It consists in a microwave-promoted acylation of the hydroxyl function of the polysaccharide with natural fatty acids, performed under solvent-free conditions. The efficient interaction of the solid reagents with the MW radiation accounts for the obtained high yielded products. The self-assembly process of the obtained compounds very fast occurred in an aqueous medium under MW-radiation, thus allowing the development of a green protocol for the nano-particles preparation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácidos Linoleicos
/
Ácidos Oléicos
/
Ácido Hialurónico
Idioma:
En
Revista:
Carbohydr Polym
Año:
2016
Tipo del documento:
Article
País de afiliación:
Italia