Synthesis of (Z)-1-(1,3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents.

Srinivasa Reddy, T; Ganga Reddy, V; Kulhari, Hitesh; Shukla, Ravi; Kamal, Ahmed; Bansal, Vipul

Srinivasa Reddy, T; Ganga Reddy, V; Kulhari, Hitesh; Shukla, Ravi; Kamal, Ahmed; Bansal, Vipul.

Afiliación

Srinivasa Reddy T; Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; IICT-RMIT Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Scienc
Ganga Reddy V; Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India.
Kulhari H; Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; IICT-RMIT Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Scienc
Shukla R; Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Science, RMIT University, Melbourne, Victoria 3000, Australia; Centre for Advanced Materials and Industrial Chemistry, School of Science, RMIT University, Melbourne, Victoria 3000, Australia.
Kamal A; Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; IICT-RMIT Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India. Electronic address: ahmedkamal@iict.res.in.
Bansal V; Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Science, RMIT University, Melbourne, Victoria 3000, Australia. Electronic address: vipul.bansal@rmit.edu.au.

Eur J Med Chem ; 117: 157-66, 2016 Jul 19.

Article en En | MEDLINE | ID: mdl-27092413

Asunto(s)

Antineoplásicos/síntesis química; Apoptosis/efectos de los fármacos; Pirazoles/síntesis química; Células A549; Antineoplásicos/farmacología; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Ensayos de Selección de Medicamentos Antitumorales; Puntos de Control de la Fase G2 del Ciclo Celular/efectos de los fármacos; Humanos; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Pirazoles/farmacología; Especies Reactivas de Oxígeno; Relación Estructura-Actividad

Palabras clave

Anti-cancer activity; Apoptosis; Cell cycle; Pyrazole

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Apoptosis / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2016 Tipo del documento: Article

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