Inflammation and Epidural-Related Maternal Fever: Proposed Mechanisms.
Anesth Analg
; 122(5): 1546-53, 2016 May.
Article
en En
| MEDLINE
| ID: mdl-27101499
ABSTRACT
Intrapartum fever is associated with excessive maternal interventions as well as higher neonatal morbidity. Epidural-related maternal fever (ERMF) contributes to the development of intrapartum fever. The mechanism(s) for ERMF has remained elusive. Here, we consider how inflammatory mechanisms may be modulated by local anesthetic agents and their relevance to ERMF. We also critically reappraise the clinical data with regard to emerging concepts that explain how anesthetic drug-induced metabolic dysfunction, with or without activation of the inflammasome, might trigger the release of nonpathogenic, inflammatory molecules (danger-associated molecular patterns) likely to underlie ERMF.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Analgesia Epidural
/
Analgesia Obstétrica
/
Fiebre
/
Inflamación
/
Anestésicos Locales
/
Complicaciones del Trabajo de Parto
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Anesth Analg
Año:
2016
Tipo del documento:
Article
País de afiliación:
Reino Unido