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Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Lui, Hansen; Zhang, Jiasheng; Makinson, Stefanie R; Cahill, Michelle K; Kelley, Kevin W; Huang, Hsin-Yi; Shang, Yulei; Oldham, Michael C; Martens, Lauren Herl; Gao, Fuying; Coppola, Giovanni; Sloan, Steven A; Hsieh, Christine L; Kim, Charles C; Bigio, Eileen H; Weintraub, Sandra; Mesulam, Marek-Marsel; Rademakers, Rosa; Mackenzie, Ian R; Seeley, William W; Karydas, Anna; Miller, Bruce L; Borroni, Barbara; Ghidoni, Roberta; Farese, Robert V; Paz, Jeanne T; Barres, Ben A; Huang, Eric J.
Afiliación
  • Lui H; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Zhang J; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Makinson SR; Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Cahill MK; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Kelley KW; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Huang HY; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Shang Y; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Oldham MC; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Martens LH; FORUM Pharmaceuticals, Waltham, MA 02451, USA.
  • Gao F; Semel Institute for Neuroscience and Human Behaviors, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Coppola G; Semel Institute for Neuroscience and Human Behaviors, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Sloan SA; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Hsieh CL; Immunology Section, San Francisco VA Medical Center and Department of Medicine, University of California, San Francisco, San Francisco, CA 94121, USA.
  • Kim CC; Department of Medicine, University of California, San Francisco, San Francisco, CA 94110, USA.
  • Bigio EH; Northwestern Alzheimer Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Weintraub S; Northwestern Alzheimer Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Mesulam MM; Northwestern Alzheimer Disease Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Mackenzie IR; Department of Pathology, University of British Columbia and Vancouver General Hospital, Vancouver, BC V5Z 1M9, Canada.
  • Seeley WW; Department of Neurology and Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Karydas A; Department of Neurology and Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Miller BL; Department of Neurology and Memory and Aging Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Borroni B; Centre for Ageing Brain and Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia 25100, Italy.
  • Ghidoni R; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio, Fatebenefratelli, Brescia 25100, Italy.
  • Farese RV; Department of Genetics and Complex Diseases, School of Public Health, Harvard University, Boston, MA 02115, USA.
  • Paz JT; Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Barres BA; Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Huang EJ; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Pathology Service (113B), San Francisco VA Medical Center, San Francisco, CA 94121, USA. Electronic address: eric.huang2@ucsf.edu.
Cell ; 165(4): 921-35, 2016 May 05.
Article en En | MEDLINE | ID: mdl-27114033
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_alzheimer_other_dementias / 6_endocrine_disorders Asunto principal: Encéfalo / Envejecimiento / Complemento C1q / Microglía / Activación de Complemento / Péptidos y Proteínas de Señalización Intercelular Límite: Animals / Humans Idioma: En Revista: Cell Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_alzheimer_other_dementias / 6_endocrine_disorders Asunto principal: Encéfalo / Envejecimiento / Complemento C1q / Microglía / Activación de Complemento / Péptidos y Proteínas de Señalización Intercelular Límite: Animals / Humans Idioma: En Revista: Cell Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos