Three-dimensional fiber-optic readout of single-neuron-resolved fluorescence in living brain of transgenic mice.
J Biophotonics
; 10(6-7): 775-779, 2017 Jun.
Article
en En
| MEDLINE
| ID: mdl-27158899
ABSTRACT
A bundle of individually addressable optical fibers is shown to enable three-dimensional optical readout from single neurons in live brain, as well as in intact brain extracted from transgenic mice. With individual fibers in the bundle being only a few microns in diameter, single neurons are readily resolved in brain images transmitted by the fiber bundle. The third dimension is added by scanning the fiber in the longitudinal direction, with the fluorescence return read out from only one of the fibers in the bundle.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Tecnología de Fibra Óptica
/
Fluorescencia
/
Neuronas
Límite:
Animals
Idioma:
En
Revista:
J Biophotonics
Asunto de la revista:
BIOFISICA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Rusia