Characterisation of a novel enterobacteria phage, CAjan, isolated from rat faeces.
Arch Virol
; 161(8): 2219-26, 2016 Aug.
Article
en En
| MEDLINE
| ID: mdl-27231007
ABSTRACT
In this study, we describe the isolation and characterisation of the novel enterobacteria phage CAjan. This phage belongs to the order Caudovirales and the family Siphoviridae. The phage possesses a linear, double-stranded DNA genome consisting of 59,670 bp with a G+C content of 44.7 % and 91 predicted open reading frames (ORFs). Putative functions were assigned to 39 of the ORFs (37.4 %). The phage structural genes were furthermore functionally characterised by LC MS/MS. CAjan, together with Escherichia phage Seurat and Escherichia phage slur01, represent a novel and genetically distinct clade of Siphoviridae phages that could be considered to constitute a new phage genus. Despite limited sequence similarity, the phages in this group share a number of other common features, including genome structure and the presence of queuosine biosynthesis genes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_neglected_diseases
/
3_zoonosis
Asunto principal:
Bacteriófagos
/
Siphoviridae
/
Heces
Límite:
Animals
Idioma:
En
Revista:
Arch Virol
Año:
2016
Tipo del documento:
Article
País de afiliación:
Dinamarca