Reducing rates of preventable HIV/AIDS-associated mortality among people living with HIV who inject drugs.
Curr Opin HIV AIDS
; 11(5): 507-513, 2016 09.
Article
en En
| MEDLINE
| ID: mdl-27254749
ABSTRACT
PURPOSE OF REVIEW The modern antiretroviral therapy (ART) era has seen substantial reductions in mortality among people living with HIV. However, HIV-positive people who inject drugs (PWIDs) continue to experience high rates of suboptimal HIV-related outcomes. We review recent findings regarding factors contributing to premature and preventable mortality among HIV-positive PWID, and describe the promise of interventions to improve survival in this group. RECENT FINDINGS:
The current leading causes of death among HIV-positive PWID are HIV/AIDS-related causes, overdose, and liver-related causes, including infection with hepatitis C virus. Elevated mortality levels in this population are driven by social-structural barriers to ART access and adherence, particularly criminalization and stigmatization of drug use. In contexts where opioid substitution therapy and ART adherence support programs are widely accessible, evidence highlights comparable levels of survival among HIV-positive PWID and people living with HIV who do not inject drugs.SUMMARY:
The life-saving benefits of ART can be realized among HIV-positive PWID when it is paired with strategies that address barriers to evidence-based medical care. Joint administration of ART and opioid substitution therapy, as well as repeal of punitive laws that criminalize drug users, are urgently needed to reduce HIV and injection-related mortality among PWID.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
/
2_ODS3
/
4_TD
/
8_ODS3_consumo_sustancias_psicoactivas
Problema de salud:
1_medicamentos_vacinas_tecnologias
/
2_cobertura_universal
/
2_enfermedades_transmissibles
/
2_sustancias_psicoativas
/
4_aids
/
8_opioid_abuse
Asunto principal:
Abuso de Sustancias por Vía Intravenosa
/
Síndrome de Inmunodeficiencia Adquirida
/
Antirretrovirales
/
Cumplimiento de la Medicación
/
Accesibilidad a los Servicios de Salud
Tipo de estudio:
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Humans
Idioma:
En
Revista:
Curr Opin HIV AIDS
Asunto de la revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Año:
2016
Tipo del documento:
Article
País de afiliación:
Canadá