[Clinical Trial of Intraoperative Tissue Identification for Breast-Conserving Surgery Using Bio-impedance Spectroscopy].
Sichuan Da Xue Xue Bao Yi Xue Ban
; 47(2): 267-71, 2016 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-27263308
ABSTRACT
OBJECTIVE:
To evaluate the effectiveness of bio-impedance spectroscopy (BIS) analysis for marginal tissue malignancy/benignancy identification during Breast-Conserving Surgery (BCS).METHODS:
A multicenter parallel-group clinical trial was conducted with the patients who received breast conserving surgery in 2 hospitals. One hundred and fifty breast tissue specimens were collected and analyzed by BIS, frozen section biopsy and paraffin section biopsy respectively. Results were compared and statistical analysis was implemented.RESULTS:
For BIS technique to identify malignant/benign marginal tissues, the sensitivity was 92.98%, and the specificity was 94.62%. The coherence of BIS results and frozen section biopsy results was significant, and the Kappa value was higher than 0.75. The mean measuring time of BIS was 2.63 min, which was shorter than frozen section biopsy (18.97 min) and paraffin section biospy (1.12 d).CONCLUSION:
BIS technique likely has high accuracy in tissue identification so has potential to be adopted as a real-time indicator for marginal tissue malignancy/benignancy identification during breast-conserving surgery.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Biopsia
/
Neoplasias de la Mama
/
Mastectomía Segmentaria
/
Espectroscopía Dieléctrica
/
Tratamientos Conservadores del Órgano
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
Zh
Revista:
Sichuan Da Xue Xue Bao Yi Xue Ban
Año:
2016
Tipo del documento:
Article