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The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation.
Sun, H; He, L; Wu, H; Pan, F; Wu, X; Zhao, J; Hu, Z; Sekhar, C; Li, H; Zheng, L; Chen, H; Shen, B H; Guo, Z.
Afiliación
  • Sun H; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • He L; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Wu H; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Pan F; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Wu X; The Second Hospital of Nanjing, The Second Affiliated Hospital of Southeast University, Nanjing, China.
  • Zhao J; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Hu Z; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Sekhar C; Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, China.
  • Li H; Department of Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA, USA.
  • Zheng L; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
  • Chen H; Department of Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA, USA.
  • Shen BH; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope, Duarte, CA, USA.
  • Guo Z; Division of Gastroenterology and Hepatology, RenJi Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Oncogene ; 36(2): 194-207, 2017 01 12.
Article en En | MEDLINE | ID: mdl-27270424
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Transformación Celular Neoplásica / Endonucleasas de ADN Solapado / Reparación del ADN / Mutación Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Transformación Celular Neoplásica / Endonucleasas de ADN Solapado / Reparación del ADN / Mutación Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: China