[Docetaxel for metastatic prostate cancer: early is better]. / Docetaxel voor gemetastaseerd prostaatcarcinoom.
Ned Tijdschr Geneeskd
; 160: D215, 2016.
Article
en Nl
| MEDLINE
| ID: mdl-27405569
ABSTRACT
Androgen deprivation therapy (ADT) has been used to treat patients with metastatic prostate cancer for many years. Docetaxel chemotherapy administered to patients with metastatic castrate-resistant prostate cancer has been standard since 2004 with a modest survival benefit. Recent data from two randomised studies (CHAARTED and STAMPEDE) demonstrate that combining ADT with docetaxel in men with hormone-naïve metastatic prostate cancer resulted in an impressive overall survival benefit of more than a year as compared with ADT alone. In a meta-analysis, the consistency of these data was confirmed. On the basis of these data, addition of six 3-weekly courses of docetaxel to ADT should be considered as standard treatment in chemo-fit patients with hormone-naïve metastatic prostate cancer.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
/
Taxoides
/
Antineoplásicos
Tipo de estudio:
Clinical_trials
Límite:
Humans
/
Male
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Año:
2016
Tipo del documento:
Article