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Associations of the CYP3A5*3 and CYP3A4*1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6ß-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese.
Chan, S W; Xiao, Y; Hu, M; Yin, O Q P; Chu, T T W; Fok, B S P; Lee, V H L; Tomlinson, B.
Afiliación
  • Chan SW; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
  • Xiao Y; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
  • Hu M; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
  • Yin OQ; School of Pharmacy, The Chinese University of Hong Kong, Hong Kong SAR, China.
  • Chu TT; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
  • Fok BS; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
  • Lee VH; School of Pharmacy, The Chinese University of Hong Kong, Hong Kong SAR, China.
  • Tomlinson B; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, NT, Hong Kong SAR, China.
J Clin Pharm Ther ; 41(5): 552-8, 2016 Oct.
Article en En | MEDLINE | ID: mdl-27511886
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Midazolam / Hidrocortisona / Biomarcadores / Citocromo P-450 CYP3A Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: J Clin Pharm Ther Asunto de la revista: FARMACIA / TERAPEUTICA Año: 2016 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Midazolam / Hidrocortisona / Biomarcadores / Citocromo P-450 CYP3A Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: J Clin Pharm Ther Asunto de la revista: FARMACIA / TERAPEUTICA Año: 2016 Tipo del documento: Article País de afiliación: China