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Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening.
Auld, Douglas S; Jimenez, Marta; Yue, Kimberley; Busby, Scott; Chen, Yu-Chi; Bowes, Scott; Wendel, Greg; Smith, Thomas; Zhang, Ji-Hu.
Afiliación
  • Auld DS; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Jimenez M; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Yue K; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Busby S; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Chen YC; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Bowes S; 2 National Center for Advancing Translational Sciences, Bethesda, MD, USA.
  • Wendel G; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Smith T; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
  • Zhang JH; 1 Novartis Institutes for Biomedical Research, Center for Proteomic Chemistry, Cambridge, MA, USA.
J Biomol Screen ; 21(10): 1075-1089, 2016 Dec.
Article en En | MEDLINE | ID: mdl-27601436
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Enzimas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Enzimas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos