Deregulation of vital mitotic kinase-phosphatase signaling in hematopoietic stem/progenitor compartment leads to cellular catastrophe in experimental aplastic anemia.

Chatterjee, Ritam; Chattopadhyay, Sukalpa; Law, Sujata

Chatterjee, Ritam; Chattopadhyay, Sukalpa; Law, Sujata.

Afiliación

Chatterjee R; Stem Cell Research and Application Unit, Department of Biochemistry and Medical Biotechnology, Calcutta School of Tropical Medicine, 108, C.R Avenue, Kolkata, 700073, West Bengal, India.
Chattopadhyay S; Stem Cell Research and Application Unit, Department of Biochemistry and Medical Biotechnology, Calcutta School of Tropical Medicine, 108, C.R Avenue, Kolkata, 700073, West Bengal, India.
Law S; Stem Cell Research and Application Unit, Department of Biochemistry and Medical Biotechnology, Calcutta School of Tropical Medicine, 108, C.R Avenue, Kolkata, 700073, West Bengal, India. msuj2002@yahoo.co.in.

Mol Cell Biochem ; 422(1-2): 121-134, 2016 Nov.

Article en En | MEDLINE | ID: mdl-27632389

Asunto(s)

Anemia Aplásica/enzimología; Proteínas de Ciclo Celular/metabolismo; Células Madre Hematopoyéticas/enzimología; Anemia Aplásica/inducido químicamente; Anemia Aplásica/patología; Animales; Busulfano/efectos adversos; Busulfano/farmacología; Ciclofosfamida/efectos adversos; Ciclofosfamida/farmacología; Femenino; Células Madre Hematopoyéticas/patología; Masculino; Ratones

Palabras clave

Aplastic anemia; Apoptosis; Cell cycle; DNA damage response; Hematopoiesis; Hematopoietic stem/progenitor cells

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Proteínas de Ciclo Celular / Anemia Aplásica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Cell Biochem Año: 2016 Tipo del documento: Article País de afiliación: India

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