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Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling.
Yuasa, Tomoyuki; Amo-Shiinoki, Kikuko; Ishikura, Shuhei; Takahara, Mitsuyoshi; Matsuoka, Takaaki; Kaneto, Hideaki; Kuroda, Akio; Matsuhisa, Munehide; Hashida, Seiichi.
Afiliación
  • Yuasa T; Division of Molecular Genetics, Institute for Enzyme Research, Tokushima University, Tokushima, Japan. yuasa.tomoyuki@tokushima-u.ac.jp.
  • Amo-Shiinoki K; Department of Community Medicine for Diabetes and Metabolic Disorders, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima-shi, Tokushima, 770-8503, Japan. yuasa.tomoyuki@tokushima-u.ac.jp.
  • Ishikura S; Division of Molecular Genetics, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
  • Takahara M; Department of Diabetes Research, Yamaguchi University School of Medicine, Yamaguchi, Japan.
  • Matsuoka T; Division of Molecular Genetics, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
  • Kaneto H; Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
  • Kuroda A; Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Matsuhisa M; Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Hashida S; Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Diabetologia ; 59(12): 2711-2721, 2016 12.
Article en En | MEDLINE | ID: mdl-27695899
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor de Insulina / Calpaína / Secretasas de la Proteína Precursora del Amiloide Límite: Humans Idioma: En Revista: Diabetologia Año: 2016 Tipo del documento: Article País de afiliación: Japón
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor de Insulina / Calpaína / Secretasas de la Proteína Precursora del Amiloide Límite: Humans Idioma: En Revista: Diabetologia Año: 2016 Tipo del documento: Article País de afiliación: Japón