Diagnosis of early colorectal cancer invasion depth by quantitative evaluation of the basal indentation in CT colonography.
Jpn J Radiol
; 34(12): 786-794, 2016 Dec.
Article
en En
| MEDLINE
| ID: mdl-27718049
ABSTRACT
OBJECTIVE:
To investigate the feasibility of diagnosing the invasion depth of early colorectal cancer (CRC) by quantitatively evaluating the basal indentation (BI)-i.e., the intestinal lateral deformity-in CT colonography (CTC). MATERIALS ANDMETHODS:
34 early CRCs (13 Tis CRCs and 21 T1 CRCs) in 32 patients who underwent a preoperative CTC were retrospectively examined. Two radiologists calculated the depth of the BI on a computed tomographic air-contrast enema (CT enema) image, the depth of the BI due to the geometric function (BI-G) on a cross-sectional multiplanar reconstruction (CS-MPR) image, and the ratio of the BI to the BI-G (i.e., the "BI ratio") for each lesion. The BI ratios of the Tis and T1 CRCs were compared.RESULTS:
The BI ratios were significantly higher in the T1 CRCs than in the Tis CRCs (p < 0.0001). The optimum cutoff value of the BI ratio for differentiating the T1 CRCs from the Tis CRCs was 1.64, with a sensitivity, specificity, and area under the curve of 90.5 %, 100 %, and 0.974, respectively.CONCLUSIONS:
We have demonstrated for the first time that quantitatively evaluating the BI can improve the accuracy of diagnosis of early CRC invasion depth.Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Colorrectales
/
Colonografía Tomográfica Computarizada
/
Detección Precoz del Cáncer
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Jpn J Radiol
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
RADIOLOGIA
/
RADIOTERAPIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Japón