Lipopolysaccharide reduces food passage rate from the crop by a prostaglandin-independent mechanism in chickens.
Br Poult Sci
; 58(1): 100-106, 2017 Feb.
Article
en En
| MEDLINE
| ID: mdl-27871194
ABSTRACT
1. We examined the effect of lipopolysaccharide (LPS), a component of Gram-negative bacteria, on food passage in the digestive tract of chickens (Gallus gallus) in order to clarify whether bacterial infection affects food passage in birds. 2. Food passage in the crop was significantly reduced by intraperitoneal (IP) injection of LPS while it did not affect the number of defecations, suggesting that LPS may affect food passage only in the upper digestive tract. 3. Similar to LPS, prostaglandin E2 (PGE2), one of the mediators of LPS, also reduced crop-emptying rate in chickens while it had no effect on the number of defecations. 4. Pretreatment with indomethacin, which is an inhibitor of cyclooxygenase (COX), a prostaglandin synthase, had no effect on LPS-induced inhibition of crop emptying. 5. IP injection of LPS did not affect the mRNA expression of COX2 in the upper digestive tract of chickens. 6. It is therefore likely that LPS and PGE2 reduced food passage rate in the crop by a prostaglandin-independent pathway in chickens.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_zoonosis
Asunto principal:
Pollos
/
Prostaglandinas
/
Lipopolisacáridos
/
Buche de las Aves
/
Digestión
Límite:
Animals
Idioma:
En
Revista:
Br Poult Sci
Año:
2017
Tipo del documento:
Article
País de afiliación:
Japón