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Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia.
Vey, Norbert; Prebet, Thomas; Thalamas, Claire; Charbonnier, Aude; Rey, Jerome; Kloos, Ioana; Liu, Emily; Luan, Ying; Vezan, Remus; Graef, Thorsten; Recher, Christian.
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  • Vey N; a Department of Hematology , Institut Paoli Calmettes, SIRIC-Marseille , Marseille , France.
  • Prebet T; b Aix-Marseille University , Marseille , France.
  • Thalamas C; c Internal Medicine Department, Section of Hematology , Yale Cancer Center at Yale University , New Haven , CT , USA.
  • Charbonnier A; d Department of Medical Pharmacology , CIC 1436, Université Toulouse Hospital, Inserm , Toulouse , France.
  • Rey J; a Department of Hematology , Institut Paoli Calmettes, SIRIC-Marseille , Marseille , France.
  • Kloos I; a Department of Hematology , Institut Paoli Calmettes, SIRIC-Marseille , Marseille , France.
  • Liu E; e Department of Oncology Research and Development , Institut de Recherches Internationales Servier , Suresnes , France.
  • Luan Y; f Biometrics, Pharmacyclics , LLC, an AbbVie Company , Sunnyvale , CA , USA.
  • Vezan R; f Biometrics, Pharmacyclics , LLC, an AbbVie Company , Sunnyvale , CA , USA.
  • Graef T; g Department of Clinical Science, Pharmacyclics , LLC, an AbbVie Company , Sunnyvale , CA , USA.
  • Recher C; g Department of Clinical Science, Pharmacyclics , LLC, an AbbVie Company , Sunnyvale , CA , USA.
Leuk Lymphoma ; 58(8): 1880-1886, 2017 08.
Article en En | MEDLINE | ID: mdl-27911138
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Síndromes Mielodisplásicos / Leucemia Mieloide Aguda / Leucemia-Linfoma Linfoblástico de Células Precursoras / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Síndromes Mielodisplásicos / Leucemia Mieloide Aguda / Leucemia-Linfoma Linfoblástico de Células Precursoras / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Francia