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Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.
Ansari, Amantullah; Satalkar, Sharad; Patil, Varshavekumar; Shete, Amit S; Kaur, Simranjeet; Gupta, Ashu; Singh, Siddhartha; Raja, Mohd; Severance, Daniel L; Bernales, Sebastián; Chakravarty, Sarvajit; Hung, David T; Pham, Son M; Herrera, Francisco J; Rai, Roopa.
Afiliación
  • Ansari A; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Satalkar S; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Patil V; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Shete AS; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Kaur S; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Gupta A; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Singh S; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Raja M; Integral BioSciences Pvt. Ltd., C-64, Hosiery Complex Phase II Extension, Noida, Uttar Pradesh 201306, India.
  • Severance DL; Schrodinger, Inc., Portland, OR, USA.
  • Bernales S; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
  • Chakravarty S; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
  • Hung DT; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
  • Pham SM; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
  • Herrera FJ; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
  • Rai R; Medivation, 525 Market Street, 36th Floor, San Francisco, CA 94105, USA. Electronic address: roopa.rai@hotmail.com.
Bioorg Med Chem Lett ; 27(2): 217-222, 2017 01 15.
Article en En | MEDLINE | ID: mdl-27923618
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína Potenciadora del Homólogo Zeste 2 / Indoles Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: India
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína Potenciadora del Homólogo Zeste 2 / Indoles Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: India