Effect of Overcrowding on Hair Corticosterone Concentrations in Juvenile Male Wistar Rats.
J Am Assoc Lab Anim Sci
; 55(6): 749-755, 2016 11.
Article
en En
| MEDLINE
| ID: mdl-27931312
In many species, chronic stress due to overcrowding during the juvenile period triggers several metabolic and behavioral pathologies in adulthood. The aim of this study was to determine whether a chronic stress condition (overcrowding) induces changes in plasma and hair corticosterone concentrations, overall growth, and organ weights in young Wistar rats. The experimental subjects were divided into 2 groups (control and overcrowded); the overcrowded subjects were exposed to overcrowding during days 38 through 65 after birth. Plasma and hair corticosterone concentrations were higher in overcrowded rats compared with control subjects. In addition, overcrowding reduced body and organ weight gains. These results demonstrate that measuring the concentration of corticosterone in hair samples is an effective, noninvasive method for monitoring chronic stress in rats.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ratas
/
Estrés Fisiológico
/
Corticosterona
/
Vivienda para Animales
Límite:
Animals
Idioma:
En
Revista:
J Am Assoc Lab Anim Sci
Asunto de la revista:
MEDICINA VETERINARIA
/
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Año:
2016
Tipo del documento:
Article
País de afiliación:
Colombia