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Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.
Nathubhai, Amit; Haikarainen, Teemu; Koivunen, Jarkko; Murthy, Sudarshan; Koumanov, Françoise; Lloyd, Matthew D; Holman, Geoffrey D; Pihlajaniemi, Taina; Tosh, David; Lehtiö, Lari; Threadgill, Michael D.
Afiliación
  • Nathubhai A; Drug and Target Discovery, Department of Pharmacy and Pharmacology, University of Bath , Claverton Down, Bath, Somerset BA2 7AY, U. K.
  • Haikarainen T; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu , PO Box 5400, 90014 Oulu, Finland.
  • Koivunen J; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu , PO Box 5400, 90014 Oulu, Finland.
  • Murthy S; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu , PO Box 5400, 90014 Oulu, Finland.
  • Koumanov F; Department of Biology and Biochemistry, University of Bath , Bath BA2 7AY, U. K.
  • Lloyd MD; Drug and Target Discovery, Department of Pharmacy and Pharmacology, University of Bath , Claverton Down, Bath, Somerset BA2 7AY, U. K.
  • Holman GD; Department of Biology and Biochemistry, University of Bath , Bath BA2 7AY, U. K.
  • Pihlajaniemi T; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu , PO Box 5400, 90014 Oulu, Finland.
  • Tosh D; Department of Biology and Biochemistry, University of Bath , Bath BA2 7AY, U. K.
  • Lehtiö L; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu , PO Box 5400, 90014 Oulu, Finland.
  • Threadgill MD; Drug and Target Discovery, Department of Pharmacy and Pharmacology, University of Bath , Claverton Down, Bath, Somerset BA2 7AY, U. K.
J Med Chem ; 60(2): 814-820, 2017 01 26.
Article en En | MEDLINE | ID: mdl-27983846
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tanquirasas / Quinazolinonas / Vía de Señalización Wnt / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Glucosa / Aminoquinolinas / Antineoplásicos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tanquirasas / Quinazolinonas / Vía de Señalización Wnt / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Glucosa / Aminoquinolinas / Antineoplásicos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article