Exploring the potential of boronic acids as inhibitors of OXA-24/40 ß-lactamase.

Werner, Josephine P; Mitchell, Joshua M; Taracila, Magdalena A; Bonomo, Robert A; Powers, Rachel A

Werner, Josephine P; Mitchell, Joshua M; Taracila, Magdalena A; Bonomo, Robert A; Powers, Rachel A.

Afiliación

Werner JP; Department of Chemistry, Grand Valley State University, Allendale, Michigan, 49401.
Mitchell JM; Department of Chemistry, Grand Valley State University, Allendale, Michigan, 49401.
Taracila MA; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, 44106.
Bonomo RA; Departments of Medicine, Pharmacology, Biochemistry and Molecular Biology, and Microbiology, Case Western Reserve University, Cleveland, Ohio, 44106.
Powers RA; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, 44106.

Protein Sci ; 26(3): 515-526, 2017 03.

Article en En | MEDLINE | ID: mdl-27997706

Asunto(s)

Ácidos Borónicos/química; Inhibidores de beta-Lactamasas/química; beta-Lactamasas/química; Cristalografía por Rayos X; Dominios Proteicos

Palabras clave

CHDL; OXA; X-ray structure; boronic acid; inhibitor; ß-lactamase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Beta-Lactamasas / Ácidos Borónicos / Inhibidores de beta-Lactamasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2017 Tipo del documento: Article

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