Three new xanthones from Swertia bimaculata and their anti-5α-reductase activity.
J Asian Nat Prod Res
; 19(8): 774-779, 2017 Aug.
Article
en En
| MEDLINE
| ID: mdl-28030961
Three new xanthones (1-3), together with five known ones (4-8), were isolated from whole herb of Swertia bimaculata. Their structures were established on the basis of detailed spectroscopic analysis (1D- and 2D-NMR, HRESIMS, UV, and IR) and comparison with data reported in the literature. New isolates were evaluated for their anti-5α-reductase activity. The results revealed that all new compounds showed weak activity with reductase inhibitions of 40.5 ± 2.8, 38.6 ± 2.5, and 48.9 ± 3.0%, respectively.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Medicamentos Herbarios Chinos
/
Swertia
/
Xantonas
/
Inhibidores de 5-alfa-Reductasa
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2017
Tipo del documento:
Article
País de afiliación:
China