Analysis of C9orf72 repeat expansion in amyotrophic lateral sclerosis patients from North India.
J Neurol Sci
; 373: 55-57, 2017 Feb 15.
Article
en En
| MEDLINE
| ID: mdl-28131227
ABSTRACT
Pathogenic expansion of a hexanucleotide repeat in C9orf72 is associated with ~30% of familial ALS and ~7% of sporadic ALS patients amongst different populations. This repeat expansion was screened in 75 ALS patients and 115 healthy individuals from North India. On analysis by repeat-primed PCR, pathogenic expansion was not observed either in ALS patients or healthy controls. These observations are similar to the findings in most of the Asian populations.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas
/
Expansión de las Repeticiones de ADN
/
Esclerosis Amiotrófica Lateral
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Neurol Sci
Año:
2017
Tipo del documento:
Article
País de afiliación:
India