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A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency.
Tharkeshwar, Arun Kumar; Trekker, Jesse; Vermeire, Wendy; Pauwels, Jarne; Sannerud, Ragna; Priestman, David A; Te Vruchte, Danielle; Vints, Katlijn; Baatsen, Pieter; Decuypere, Jean-Paul; Lu, Huiqi; Martin, Shaun; Vangheluwe, Peter; Swinnen, Johannes V; Lagae, Liesbet; Impens, Francis; Platt, Frances M; Gevaert, Kris; Annaert, Wim.
Afiliación
  • Tharkeshwar AK; Laboratory for Membrane Trafficking, VIB Center for Brain &Disease Research, KU Leuven, Department of Neurosciences, Leuven, Belgium.
  • Trekker J; Department of Life Science Technology, imec, Leuven, Belgium.
  • Vermeire W; VIB Medical Biotechnology Center &Department of Biochemistry, UGent, Ghent, Belgium.
  • Pauwels J; Department of Life Science Technology, imec, Leuven, Belgium.
  • Sannerud R; Biomedical MRI, Department of Imaging and Pathology, KU Leuven, Leuven 3000, Belgium.
  • Priestman DA; Laboratory for Membrane Trafficking, VIB Center for Brain &Disease Research, KU Leuven, Department of Neurosciences, Leuven, Belgium.
  • Te Vruchte D; VIB Medical Biotechnology Center &Department of Biochemistry, UGent, Ghent, Belgium.
  • Vints K; Laboratory for Membrane Trafficking, VIB Center for Brain &Disease Research, KU Leuven, Department of Neurosciences, Leuven, Belgium.
  • Baatsen P; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Decuypere JP; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Lu H; VIB Bio-imaging core VIB Center for Brain &Disease Research, Leuven, Belgium.
  • Martin S; VIB Bio-imaging core VIB Center for Brain &Disease Research, Leuven, Belgium.
  • Vangheluwe P; Laboratory for Membrane Trafficking, VIB Center for Brain &Disease Research, KU Leuven, Department of Neurosciences, Leuven, Belgium.
  • Swinnen JV; Laboratory for Membrane Trafficking, VIB Center for Brain &Disease Research, KU Leuven, Department of Neurosciences, Leuven, Belgium.
  • Lagae L; Laboratory of Cellular Transport Systems, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Impens F; Laboratory of Cellular Transport Systems, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Platt FM; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, KU Leuven, Leuven, Belgium.
  • Gevaert K; Department of Life Science Technology, imec, Leuven, Belgium.
  • Annaert W; Department of Physics, Solid State Physics and Magnetism, KU Leuven, Leuven, Belgium.
Sci Rep ; 7: 41408, 2017 01 30.
Article en En | MEDLINE | ID: mdl-28134274
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Proteómica / Metabolismo de los Lípidos / Lisosomas Límite: Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glicoproteínas de Membrana / Proteómica / Metabolismo de los Lípidos / Lisosomas Límite: Humans Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Bélgica