The effects of 2% ibopamine eye drops on the intraocular pressure and pupil motility of patients with open-angle glaucoma.
Eur J Ophthalmol
; 14(6): 508-513, 2004.
Article
en En
| MEDLINE
| ID: mdl-28221659
ABSTRACT
PURPOSE:
Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its a-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders.METHODS:
This is a randomized, crossover, open-labeled, two- center study. Forty patients (20 open-angle glaucoma patients and 20 healthy subjects) were treated with ibopamine 2% eye drops and phenylephrine 10% eye drops.RESULTS:
Ibopamine induced a significant increase in IOP only in glaucomatous eyes (p<0.001) without a significant hypertensive effect in normal eyes. Ibopamine and phenylephrine showed a similar mydriatic activity but ibopamine was able to induce an hypertensive effect only in glaucomatous eyes.CONCLUSIONS:
The results confirm the use of ibopamine as provocative test in detection of hydrodynamic disorders.(Eur J Ophthalmol 2004; 14 #-13).
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Clinical_trials
Idioma:
En
Revista:
Eur J Ophthalmol
Asunto de la revista:
OFTALMOLOGIA
Año:
2004
Tipo del documento:
Article