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Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents.
Vreese, Rob De; Kock, Carmen de; Smith, Peter J; Chibale, Kelly; D'hooghe, Matthias.
Afiliación
  • Vreese R; SynBioC Research Group, Department of Sustainable Organic Chemistry & Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.
  • Kock C; Division of Pharmacology, Department of Medicine, University of Cape Town, K45, OMB Groote Schuur Hospital, Observatory 7925, South Africa.
  • Smith PJ; Division of Pharmacology, Department of Medicine, University of Cape Town, K45, OMB Groote Schuur Hospital, Observatory 7925, South Africa.
  • Chibale K; South African Medical Research Council Drug Discovery & Development Research Unit, Department of Chemistry & Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa.
  • D'hooghe M; SynBioC Research Group, Department of Sustainable Organic Chemistry & Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.
Future Med Chem ; 9(4): 357-364, 2017 03.
Article en En | MEDLINE | ID: mdl-28263085
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_malaria / 3_neglected_diseases Asunto principal: Plasmodium falciparum / Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Ácidos Hidroxámicos / Antimaláricos Límite: Animals / Humans Idioma: En Revista: Future Med Chem Año: 2017 Tipo del documento: Article País de afiliación: Bélgica
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_malaria / 3_neglected_diseases Asunto principal: Plasmodium falciparum / Inhibidores de Histona Desacetilasas / Histona Desacetilasas / Ácidos Hidroxámicos / Antimaláricos Límite: Animals / Humans Idioma: En Revista: Future Med Chem Año: 2017 Tipo del documento: Article País de afiliación: Bélgica