Salivary secretory IgA concentration and dental caries in children with Down syndrome.
Spec Care Dentist
; 37(3): 115-119, 2017 May.
Article
en En
| MEDLINE
| ID: mdl-28263433
ABSTRACT
PURPOSE:
To evaluate the relationship between salivary secretory immunoglobulin A (sIgA) concentration and dental caries in children with Down syndrome (DS) and compare it with findings in non-DS children.METHODS:
The sample comprised 61 DS children and 52 non-DS children, aged 6 to 14 years. Caries experience, plaque index (PI), and gingival bleeding index (GBI) were recorded. Saliva samples were collected from all children. Total salivary sIgA concentrations were determined using an enzymatic assay method.RESULTS:
Caries experience in primary and permanent dentitions were similar in DS and non-DS children. However, PI and GBI values were significantly lower in DS compared to non-DS children. DS children had higher salivary sIgA concentrations compared to non-DS children. No difference in sIgA concentration was observed between children with and without caries experience in either group.CONCLUSIONS:
DS children have higher salivary sIgA concentrations than non-DS children. However, this finding did not correlate with caries experience in the study population.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saliva
/
Inmunoglobulina A Secretora
/
Síndrome de Down
/
Caries Dental
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Spec Care Dentist
Año:
2017
Tipo del documento:
Article
País de afiliación:
Brasil