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Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms.
Nguyen, Tri; Parker, Rebecca; Hawkins, Elisa; Holkova, Beata; Yazbeck, Victor; Kolluri, Akhil; Kmieciak, Maciej; Rahmani, Mohamed; Grant, Steven.
Afiliación
  • Nguyen T; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Parker R; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Hawkins E; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Holkova B; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Yazbeck V; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Kolluri A; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Kmieciak M; Massey Cancer Center, Virginia Commonwealth University Health Sciences Center, Richmond, VA, USA.
  • Rahmani M; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
  • Grant S; Division of Hematology/Oncology, Department of Internal Medicine, Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA, USA.
Oncotarget ; 8(19): 31478-31493, 2017 May 09.
Article en En | MEDLINE | ID: mdl-28416758
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_lymphomas_multiple_myeloma Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Inhibidores de Proteínas Quinasas / Inhibidores de Histona Desacetilasas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_lymphomas_multiple_myeloma Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Inhibidores de Proteínas Quinasas / Inhibidores de Histona Desacetilasas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos