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Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.
Alekseyenko, Artyom A; Walsh, Erica M; Zee, Barry M; Pakozdi, Tibor; Hsi, Peter; Lemieux, Madeleine E; Dal Cin, Paola; Ince, Tan A; Kharchenko, Peter V; Kuroda, Mitzi I; French, Christopher A.
Afiliación
  • Alekseyenko AA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Walsh EM; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Zee BM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Pakozdi T; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Hsi P; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Lemieux ME; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115.
  • Dal Cin P; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Ince TA; Bioinfo, Plantagenet, ON, Canada K0B 1L0.
  • Kharchenko PV; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Kuroda MI; Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136.
  • French CA; Braman Family Breast Cancer Institute, University of Miami Miller School of Medicine, Miami, FL 33136.
Proc Natl Acad Sci U S A ; 114(21): E4184-E4192, 2017 05 23.
Article en En | MEDLINE | ID: mdl-28484033
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Factores de Transcripción / Proteínas Nucleares / Cromatina / Carcinoma de Células Escamosas / Proteínas de Fusión Oncogénica / Proteínas Oncogénicas / Proteína p300 Asociada a E1A / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Factores de Transcripción / Proteínas Nucleares / Cromatina / Carcinoma de Células Escamosas / Proteínas de Fusión Oncogénica / Proteínas Oncogénicas / Proteína p300 Asociada a E1A / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article